INCT

Publicações dos pesquisadores do INCT Envelhecimento e Doenças Genéticas

Julho de 2017 a junho de 2018:

1. de Albuquerque JAT, Banerjee PP, Castoldi A, Ma R, Zurro NB, Ynoue LH, Arslanian C, Barbosa-Carvalho MUW, Correia-Deur JEM, Weiler FG, Dias-da-Silva MR, Lazaretti-Castro M, Pedroza LA, Câmara NOS, Mace E, Orange JS, Condino-Neto A. The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages. Front Immunol. 2018 Mar 21;9:567. doi: 10.3389/fimmu.2018.00567. eCollection 2018.

2. Almeida MF, Silva CM, Chaves RS, Lima NCR, Almeida RS, Melo KP, Demasi M, Fernandes T, Oliveira EM, Netto LES, Cardoso SM, Ferrari MFR. Effects of mild running on substantia nigra during early neurodegeneration. J Sports Sci. 2018 Jun;36(12):1363-1370. doi: 10.1080/02640414.2017.1378494. Epub 2017 Sep 12.

3. Alvizi L, Ke X, Brito LA, Seselgyte R, Moore GE, Stanier P, Passos-Bueno MR. Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects. Sci Rep. 2017 26;7(1):2441. doi: 10.1038/s41598-017-02721-0.

4. Araujo BHS, Kaid C, De Souza JS, Gomes da Silva S, Goulart E, Caires LCJ, Musso CM, Torres LB, Ferrasa A, Herai R, Zatz M, Okamoto OK, Cavalheiro EA. Down Syndrome iPSC-Derived Astrocytes Impair Neuronal Synaptogenesis and the mTOR Pathway In Vitro. Mol Neurobiol. 2017 Nov 11. doi: 10.1007/s12035-017-0818-6. [Epub ahead of print]

5. de Araujo CM, Zugman A, Swardfager W, Belangero SIN, Ota VK, Spindola LM, Hakonarson H, Pellegrino R, Gadelha A, Salum GA, Pan PM, de Moura LM, Del Aquilla M, Picon FA, Amaro E Jr, Sato JR, Brietzke E, Grassi-Oliveira R, Rohde LAP, Miguel EC, Bressan RA, Jackowski AP. Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence. Journal of Psychiatric Research, v. 98, p. 51-58, 2018.

6. Assoni AF, Castello G, Valadares M, Beccari M, Gomes J, Pelatti M, Mitne-Neto M, Carvalho VM, Zatz M. Different donors Mesenchymal Stromal Cells secretomes reveal heterogeneous profile of relevance for therapeutic use. Stem Cells Dev. 2017 1;26(3):206-214

7. Bertola DR, Hsia G, Alvizi L, Gardham A, Wakeling EL, Yamamoto GL, Honjo RS, Oliveira LAN, Di Francesco RC, Perez BA, Kim CA, Passos-Bueno MR. Richieri-Costa-Pereira syndrome: Expanding its phenotypic and genotypic spectrum. Clin Genet. 2018 Apr;93(4):800-811. doi: 10.1111/cge.13169. Epub 2018 Feb 20.

8. Bertola DR, Yamamoto G, Buscarilli M, Jorge A, Passos-Bueno MR, Kim C. The recurrent PPP1CB mutation p.Pro49Arg in an additional Noonan-like syndrome individual: Broadening the clinical phenotype. Am J Med Genet A. 2017;173(3):824-828. doi: 10.1002/ajmg.a.38070.

9. Cabral-Marques O, França TT, Al-Sbiei A, Schimke LF, Khan TA, Feriotti C, da Costa TA, Junior OR, Weber CW, Ferreira JF, Tavares FS, Valente C, Di Gesu RSW, Iqbal A, Riemekasten G, Amarante-Mendes GP, Marzagão Barbuto JA, Costa-Carvalho BT, Pereira PVS, Fernandez-Cabezudo MJ, Calich VLG, Notarangelo LD, Torgerson TR, Al-Ramadi BK, Ochs HD, Condino-Neto A. CD40 ligand deficiency causes functional defects of peripheral neutrophils that are improved by exogenous IFN-γ. J Allergy Clin Immunol. 2018 Mar 5. pii: S0091-6749(18)30318-X. doi: 10.1016/j.jaci.2018.02.026. [Epub ahead of print]

10. Caires-Júnior LC, Goulart E, Melo US, Araujo BSH, Alvizi L, Soares-Schanoski A, de Oliveira DF, Kobayashi GS, Griesi-Oliveira K, Musso CM, Amaral MS, da Silva LF, Astray RM, Suárez-Patiño SF, Ventini DC, Gomes da Silva S, Yamamoto GL, Ezquina S, Naslavsky MS, Telles-Silva KA, Weinmann K, van der Linden V, van der Linden H, de Oliveira JMR, Arrais NRM, Melo A, Figueiredo T, Santos S, Meira JCG, Passos SD, de Almeida RP, Bispo AJB, Cavalheiro EA, Kalil J, Cunha-Neto E, Nakaya H, Andreata-Santos R, de Souza Ferreira LC, Verjovski-Almeida S, Ho PL, Passos-Bueno MR, Zatz M. Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells. Nat Commun. 2018 Feb 2;9(1):475. doi: 10.1038/s41467-017-02790-9.

11. Ceroni JR, Yamamoto GL, Honjo RS, Kim CA, Passos-Bueno MR, Bertola DR. Large deletion in PIGL: a common mutational mechanism in CHIME syndrome? Genet Mol Biol. 2018 Jan-Mar;41(1):85-91. doi: 10.1590/1678-4685-GMB-2017-0172. Epub 2018 Feb 19.

12. Coatti GC, Frangini M, Valadares MC, Gomes JP, Lima NO, Cavaçana N, Assoni AF, Pelatti MV, Birbrair A, de Lima ACP, Singer JM, Rocha FMM, Da Silva GL, Mantovani MS, Macedo-Souza LI, Ferrari MFR, Zatz M. Pericytes Extend Survival of ALS SOD1 Mice and Induce the Expression of Antioxidant Enzymes in the Murine Model and in IPSCs Derived Neuronal Cells from an ALS Patient. Stem Cell Rev. 2017 Jul 14. doi: 10.1007/s12015-017-9752-2. [Epub ahead of print]

13. Cotta A, Paim JF, Pavanello RCM, Nogueira L, Leão LG, Xavier-Neto R, Navarro MM, Carvalho E, Valicek J, Silveira EB, Takata RI, Vainzof M. Central core myopathy with autophagy. Muscle Nerve. 2017 Aug;56(2):E8-E9. doi: 10.1002/mus.25594. Epub 2017 Mar 21.

14. D'Angelo CS, Varela MC, de Castro CIE, Otto PA, Perez ABA, Lourenço CM, Kim CA, Bertola DR, Kok F, Garcia-Alonso L, Koiffmann CP. Chromosomal microarray analysis in the genetic evaluation of 279 patients with syndromic obesit . Mol Cytogenet. 2018 Feb 5;11:14. doi: 10.1186/s13039-018-0363-7. eCollection 2018.

15. Dernowsek JA, Pereira MC, Fornari TA, Macedo C, Assis AF, Donate PB, Bombonato-Prado KF, Passos-Bueno MR, Passos GA. Posttranscriptional Interaction between miR-450a-5p and miR-28-5p and STAT1 mRNA Triggers Osteoblastic Differentiation of Human Mesenchymal Stem Cells. J Cell Biochem. 2017 13. doi: 10.1002/jcb.26060. [Epub ahead of print]

16. Ducci RD, Scola RH, Lorenzoni PJ, Kay CSK, Blood MRY, Leão LG, Vainzof M, Werneck LC. Immune-mediated rippling muscle disease in a patient with treated hypothyroidism. J Neurol Sci. 2017 Dec 15;383:53-55. doi: 10.1016/j.jns.2017.10.016. Epub 2017 Oct 13.

17. Farizatto KLG, Ikonne US, Almeida MF, Ferrari MFR, Bahr BA. A β42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways. PLoS One, 12, p. e0182895, 2017.

18. Ferreira LD, Borges-Medeiros RL, de Oliveira, JRM. More than meets the eye: Searching for additional findings in primary brain calcification. Journal of the Neurological Sciences. , v.379, p.117 - 118, 2017.

19. França TT, Leite LFB, Maximo TA, Lambert CG, Zurro NB, Forte WCN, Condino-Neto A. A Novel de Novo Mutation in the CD40 Ligand Gene in a Patient With a Mild X-Linked Hyper-IgM Phenotype Initially Diagnosed as CVID: New Aspects of Old Diseases. Front Pediatr. 2018 May 4;6:130. doi: 10.3389/fped.2018.00130. eCollection 2018.

20. Gérardin P, Ramos RC, Jungmann P, de Oliveira JRM, Amara A, Gressens P. Zika epidemic: a step towards understanding the infectious causes of microcephaly? Lancet Infectious Diseases , v. 18, p. 15-16, 2018.

21. Gomes JPA, Assoni AF, Pelatti M, Coatti G, Okamoto OK, Zatz M. Deepening a Simple Question: Can MSCs Be Used to Treat Cancer? Anticancer Res. 2017 Sep;37(9):4747-4758. Review.

22. Gomes KF, Santos AS, Semzezem C, Correia MR, Brito LA, Ruiz MO, Fukui RT, Matioli SR, Passos-Bueno MR, Silva ME. The influence of population stratification on genetic markers associated with type 1 diabetes. Sci Rep. 2017 6;7:43513. doi: 10.1038/srep43513.

23. Gomes KF, Semzezem C, Batista R, Fukui RT, Santos AS, Correia MR, Passos-Bueno MR, Silva ME. Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans. Sci Rep. 2017 16;7(1):207. doi: 10.1038/s41598-017-00307-4.

24. Hirata FCC, Sato, JR, Vieira, G, Lucato LT, Leite CC, Bor-Seng-Shu, E, Pastorello, BF, Otaduy MCG, Chaim KT, Campanholo KR, Novaes NP, Melo, LM, Gonçalves, MR, do Nascimento FBP, Teixeira, MJ, Barbosa, ER, Amaro Junior, E, Cardoso EF. Substantia nigra fractional anisotropy is not a diagnostic biomarker of Parkinson’s disease: A diagnostic performance study and meta-analysis. European Radiology, v.27, p.2640 - 2648, 2017.

25. Ishiy FAA, Fanganiello RD, Kobayashi GS, Kague E, Kuriki PS, Passos-Bueno MR. CD105 is regulated by hsa-miR-1287 and its expression is inversely correlated with osteopotential in SHED. Bone. 2018 Jan;106:112-120. doi: 10.1016/j.bone.2017.10.014. Epub 2017 Oct 13.

26. Jensen, N, Schroder, HD, Hejbol, EK, Thomsen, JS, Brüel, A, Larsen, FT, Vinding, MC, Orlowski, D,; Füchtbauer, Ernst-Martin, de Oliveira JRM, Pedersen, L. Mice knocked out for the primary brain calcification associated gene Slc20a2 show unimpaired pre-natal survival but retarded growth and nodules in the brain that grow and calcify over time. American Journal of Pathology . v.00, p.00 - 00, 2018. 2018 May 24. pii: S0002-9440(17)30721-6. doi: 10.1016/j.ajpath.2018.04.010

27. Kague E, Witten PE, Soenens M, Campos CL, Lubiana T, Fisher S, Hammond C, Brown KR, Passos-Bueno MR, Huysseune A. Zebrafish sp7 mutants show tooth cycling independent of attachment, eruption and poor differentiation of teeth. Dev Biol. 2018 Mar 15;435(2):176-184. doi: 10.1016/j.ydbio.2018.01.021. Epub 2018 Feb 2.

28. Kaid C, Goulart E, Caires-Júnior LC, Araujo BHS, Soares-Schanoski A, Siqueira Bueno HM, Silva KAT, Astray RM, Assoni AF, Ribeiro Júnior AF, Ventini DC, Puglia ALP, Gomes RP, Zatz M, Okamoto OK. Zika virus selectively kills aggressive human embryonal CNS tumor cells in vitro and in vivo. Cancer Res. 2018 Apr 26.

29. Lim ET, Uddin M, De Rubeis S, Chan Y, Kamumbu AS, Zhang X, D'Gama AM, Kim SN, Hill RS, Goldberg AP, Poultney C, Minshew NJ, Kushima I, Aleksic B, Ozaki N, Parellada M, Arango C, Penzol MJ, Carracedo A, Kolevzon A, Hultman CM, Weiss LA, Fromer M, Chiocchetti AG, Freitag CM; Autism Sequencing Consortium (Passos-Bueno, MR), Church GM, Scherer SW, Buxbaum JD, Walsh CA. Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder. Nat Neurosci. 2017 Sep;20(9):1217-1224. doi: 10.1038/nn.4598. Epub 2017 Jul 17

30. Lima-Pardini AC, Neto RMA, Coelho DB, Boffino CC, Shergill SS, Souza CO, Brant R, Barbosa ER, Cardoso EF, Teixeira LA, Cohen RG, Horak FB, Amaro Jr E. An fMRI-compatible force measurement system for the evaluation of the neural correlates of step initiation. Scientific Reports. , v.7, p.43088 - , 2017.

31. Liu, J, Heinsen, H, Grinberg, LT, Alho, E, Amaro Jr , E, C A Pasqualucci, CA, Rüb, U, Seidel, K, den Dunnen, W, Arzberger , T, Schmitz C, Kiessling, MC, Bader B, A Danek, A. Pathoarchitectonics of the cerebral cortex in chorea-acanthocytosis and HD. Neuropathology and Applied Neurobiology. , v.x, p.x - , 2018. (IF=5,3)

32. Liu J, Heinsen H, Grinberg LT, Alho E, Amaro Jr E, Pasqualucci CA, Rüb U, den Dunnen, W, Arzberger T, Schmitz C, Kiessling M, Bader B, Danek A. Subcortical neurodegeneration in chorea: More differences than similarities between chorea-acanthocytosis and Huntington's disease. Parkinsonism & Related Disorders. , v.x, p.x - , 2018. (IF=4,5)

33. Lostal W, Urtizberea JA, Richard I; calpain 3 study group (Mariz Vainzof) . 233rd ENMC International Workshop:: Clinical Trial Readiness for Calpainopathies, Naarden, The Netherlands, 15-17 September 2017. Neuromuscul Disord. 2018 Jun;28(6):540-549. doi: 10.1016/j.nmd.2018.03.010. Epub 2018 Mar 28. No abstract available.

34. Lukasova, K , Nucci, MP, Netto, RMA, VIEIRA, G , Sato, JR. ; Amaro Jr E. Predictive saccades in children and adults: A combined fMRI and eye tracking study. PLoS One, v. 13, p. e0196000, 2018

35. Masotti C, Brito LA, Nica AC, Ludwig KU, Nunes K, Savastano CP, Malcher C, Ferreira SG, Kobayashi GS, Bueno DF, Alonso N, Franco D, Rojas-Martinez A, Dos Santos SE, Galante PA, Meyer D, Hünemeier T, Mangold E, Dermitzakis ET, Passos-Bueno MR. MRPL53, a New Candidate Gene for Orofacial Clefting, Identified Using an eQTL Approach. J Dent Res. 2018 Jan;97(1):33-40. doi:

36. Melo,TQ, Van Zomeren, KC, Ferrari MFR, Boddeke, HWGM, Copray, JCVM. (2017) . Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson’s disease. Experimental Brain Research, 235 (3), 731-742.

37. Miller EE, Kobayashi GS, Musso CM, Allen M, Ishiy FA, de Caires Junior LC, Guimarães ES, Griesi-Oliveira K, Zechi-Ceide RM, Richieri-Costa A, Bertola DR, Passos-Bueno MR, Silver DL. EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira Syndrome. Hum Mol Genet. 2017 2. doi: 10.1093/hmg/ddx078. [Epub ahead of print]

38. Miot C, Imai K, Imai C, Mancini AJ, Kucuk ZY, Kawai T, Nishikomori R, Ito E, Pellier I, Dupuis Girod S, Rosain J, Sasaki S, Chandrakasan S, Pachlopnik Schmid J, Okano T, Colin E, Olaya-Vargas A, Yamazaki-Nakashimada M, Qasim W, Espinosa Padilla S, Jones A, Krol A, Cole N, Jolles S, Bleesing J, Vraetz T, Gennery AR, Abinun M, Güngör T, Costa-Carvalho B, Condino-Neto A, Veys P, Holland SM, Uzel G, Moshous D, Neven B, Blanche S, Ehl S, Döffinger R, Patel SY, Puel A, Bustamante J, Gelfand EW, Casanova JL, Orange JS, Picard C. Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG/NEMO mutations. Blood. 2017 Sep 21;130(12):1456-1467. doi: 10.1182/blood-2017-03-771600. Epub 2017 Jul 5. (IF=13,1)

39. Moraes L.A.G de, E.B. Felestrino, R.A.B Assis, D. Matos, J.C. Lima, L.A. Lima, N.F. Almeida, J.C. Setubal, C.C.M. Garcia, and L.M. Moreira. TabPath: interactive Tables for Metabolic Pathway analysis. Bioinformatics, 34(6):1040-1042, 2018.

40. Moura, DAP, Lemos, Roberta R, de Oliveira, JRM New Data from Pdfgb ret/ret Mutant Mice Might Lead to a Paradoxical Association Between Brain Calcification, Pericytes Recruitment and BBB Integrity. Journal of Molecular Neuroscience, 2017. Dec;63(3-4):419-421. doi: 10.1007/s12031-017-0992-z

41. Naslavsky MS, Yamamoto GL, de Almeida TF, Ezquina SAM, Sunaga DY, Pho N, Bozoklian D, Sandberg TOM, Brito LA, Lazar M, Bernardo DV, Amaro E Jr, Duarte YAO, Lebrão ML, Passos-Bueno MR, Zatz M. Exomic variants of an elderly cohort of Brazilians in the ABraOM database. Hum Mutat. 2017 23. doi: 10.1002/humu.23220. [Epub ahead of print]

42. Nicolas G, Ramos EM, Carecchio M, Lemos R, Ferreira J, Legati A, Sears R, Hsu Chan S, Panteghini C, Magistrelli L, Salsano E, Esposito S, Taroni F, Richard AC, Tranchant C, Anheim M, Ayrignac X, Goizet C, Vidailhet M, Maltete D, Wallon D, Frébourg T, Pimentel L, Geschwind D, Vanakker O, Galasko D, Fogel B, Micheil IA, Ross A, Dobyns W, Alcantara D, O'Driscoll M, Hannequin D, Campion D, de Oliveira JRM, Barbara Garavaglia, and Giovanni Coppola. Primary brain calcification: an international study reporting novel variants and associated phenotypes. In Press, 2018. European Journal of Human Genetics.

43. NicolasI G, Marguet, F,Laquerriere A, Laquerrierre, A, de Oliveira, JRM; Hannequin, D. Microangiopathy in primary familial brain calcification: Evidence from skin biopsies. Neurology Genetics. , v.3, p.e134 - , 2017.

44. Nunes BG, Loures FV, Bueno HMS, Cangussu EB, Goulart E, Coatti GC, Caldini EG, Condino-Neto A, Zatz M. Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin–utrophin double knockout mice. Eur J Hum Genet. 2017 Dec;25(12):1388-1396. doi: 10.1038/s41431-017-0017-y. Epub 2017 Oct 27.

45. Paez-Espino D, I-Min Chen, K. Palaniappan, A. Ratner, K. Chu, E. Szeto, M. Pillay, J. Huang, V. Markowitz, T. Nielsen, M. Huntemann, T. Reddy, G. Pavlopoulos, M. Sullivan, B. Campbell, F. Chen, K. McMahon, S. Hallam, V. Denef, R. Cavicchioli, S. Caffrey, W. Streit, J. Webster, K. Handley, G. Salekdeh, N. Tsesmetzis, Setubal JC, P. Pope, W. Liu, A. Rivers, N. Ivanova, N. Kyrpides. IMG/VR: A database of cultured and uncultured DNA Viruses and Retroviruses. Nucleic Acids Research, 45 (D1), D457-D465 (database (IF-10)

46. Perazzio SF, Soeiro-Pereira PV, Dos Santos VC, de Brito MV, Salu B, Oliva MLV, Stevens AM, de Souza AWS, Ochs HD, Torgerson TR, Condino-Neto A, Andrade LEC. Soluble CD40L is associated with increased oxidative burst and neutrophil extracellular trap release in Behçet's disease. Arthritis Res Ther. 2017 Oct 19;19(1):235. doi: 10.1186/s13075-017-1443-5. (IF=4,2)

47. Pimentel LF, Lemos, R.R, de Oliveira, JRM. Phosphate Transporters Expression in Patients with Primary Familial Brain Calcifications. Journal of Molecular Neuroscience. 2017. 2017 Aug;62(3-4):276-280. doi: 10.1007/s12031-017-0934-9.

48. Preite NW, Feriotti C, Souza de Lima D, da Silva BB, Condino-Neto A, Pontillo A, Calich VLG, Loures FV. The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells. Front Immunol. 2018 Mar 20;9:464. doi: 10.3389/fimmu.2018.00464. eCollection 2018. (IF=6,4)

49. Reis VN, Kitajima JP, Tahira AC, Feio-Dos-Santos AC, Fock RA, Lisboa BC,Simões SN, Krepischi AC, Rosenberg C, Lourenço NC, Passos-Bueno MR, Brentani H. Integrative Variation Analysis Reveals that a Complex Genotype May SpecifyPhenotype in Siblings with Syndromic Autism Spectrum Disorder. PLoS One. 2017 24;12(1):e0170386. doi: 10.1371/journal.pone.0170386. eCollection 2017

50. Ribeiro AL, Kaid C, Silva PBG, Cortez BA, Okamoto OK. Inhibition of Lysyl Oxidases Impairs Migration and Angiogenic Properties of Tumor-Associated Pericytes. Stem Cells Int. 2017;2017:4972078. doi: 10.1155/2017/4972078. Epub 2017 May 3. PubMed PMID: 28553358; PubMed Central PMCID: PMC5434472.

51. Rodini CO, Gonçalves da Silva PB, Assoni AF, Carvalho VM, Okamoto OK. Mesenchymal stem cells enhance tumorigenic properties of human glioblastoma through independent cell-cell communication mechanisms. Oncotarget. 2018 May 15;9(37):24766-24777. doi: 10.18632/oncotarget.25346. eCollection 2018 May 15.PubMed PMID: 29872504; PubMed Central PMCID: PMC5973871.

52. Romanelli Tavares VL, Zechi-Ceide RM, Bertola DR, Gordon CT, Ferreira SG, Hsia GS, Yamamoto GL, Ezquina SA, Kokitsu-Nakata NM, Vendramini-Pittoli S, Freitas RS, Souza J, Raposo-Amaral CA, Zatz M, Amiel J, Guion-Almeida ML, Passos-Bueno MR. Targeted molecular investigation in patients within the clinical spectrum of Auriculocondylar syndrome . Am J Med Genet A. 2017;173(4):938-945. doi: 10.1002/ajmg.a.38101.

53. Santos JM, Andrade PV, Galleni L, Vainzof M, Sobreira CFR, Schmidt B, Oliveira ASB, Amaral JLG, Silva HCA. Idiopathic hyperCKemia and malignant hyperthermia susceptibility. Can J Anaesth. 2017 Dec;64(12):1202-1210. doi: 10.1007/s12630-017-0978-x. Epub 2017 Sep 26.

54. Santos Matioli MNP, Suemoto CK, Rodriguez RD, Farias DS, da Silva MM, Leite REP, Ferretti-Rebustini REL, Farfel JM, Pasqualucci CA, Jacob Filho W, Arvanitakis Z, Naslavsky MS, Zatz M, Grinberg LT, Nitrini R. Diabetes is Not Associated with Alzheimer's Disease Neuropathology. J Alzheimers Dis. 2017;60(3):1035-1043. doi: 10.3233/JAD-170179.

55. Schactae AL, Palmas D, Michels M, Generoso JS, Barichello T, Dal-Pizzol F, Vainzof M, Comim CM. Congenital Muscular Dystrophy 1D Causes Matrix Metalloproteinase Activation And Blood-Brain Barrier Impairment. Curr Neurovasc Res. 2017;14(1):60-64. doi: 10.2174/1567202613666161201204549.

56. Schimke LF, Hibbard J, Martinez-Barricarte R, Khan TA, de Souza Cavalcante R, Borges de Oliveira Junior E, Takahashi França T, Iqbal A, Yamamoto G, Arslanian C, Feriotti C, Costa TA, Bustamante J, Boisson-Dupuis S, Casanova JL, Marzagao Barbuto JA, Zatz M, Poncio Mendes R, Garcia Calich VL, Ochs HD, Torgerson TR, Cabral-Marques O, Condino-Neto A. Paracoccidioidomycosis Associated With a Heterozygous STAT4 Mutation and Impaired IFN-γ Immunity. J Infect Dis. 2017 Dec 19;216(12):1623-1634. doi: 10.1093/infdis/jix522.

57. Setubal JC. and P.F. Stadler. Gene Phylogenies and Orthologous Groups . Methods in Molecular Biology, v. 1704, pp. 1-28. Springer New York, 2018.

58. Setubal J.C., N.F. Almeida, A.R. Wattam. Comparative Genomics for Prokaryotes. Methods in Molecular Biology, v. 1704, pp. 55-78. Springer New York, 2018.

59. Shigaeff, N, Amaro Jr, Edson; Franco, FGM, Jacinto, A F, Chiochetta, G;, Cendoroglo, MS, Citero, VA. Functional magnetic resonance imaging response as an early biomarker of cognitive decline in elderly patients with metabolic syndrome . Archives of Gerontology and Geriatrics. , v.73, p.1 - 7, 2017. (IF=2)

60. Silva L.F. da, F. Beckedorff, A.C. Ayupe, M.S. Amaral, V. Mesel, A. Videira, E.M. Reis, J.C.Setubal, S. Verjovski-Almeida. Chromatin landscape distinguishes the genomic loci of hundreds of androgen-receptor-associated lincRNAs from the loci of non-associated lincRNAs. Frontiers in Genetics, section RNA, 9(132), 2018. (if=4)

61. Silva MC, Magalhães TA, Meira ZM, Rassi CH, Andrade AC, Gutierrez PS, Azevedo CF, Gurgel-Giannetti J, Vainzof M, Zatz M, Kalil-Filho R, Rochitte CE. Myocardial Fibrosis Progression in Duchenne and Becker Muscular Dystrophy: A Randomized Clinical Trial. JAMA Cardiol. 2017 1;2(2):190-199. doi: 10.1001/jamacardio.2016.4801.

62. Silva PBG, Teixeira Dos Santos MC, Rodini CO, Kaid C, Pereira MCL, Furukawa G, da Cruz DSG, Goldfeder MB, Rocha CRR, Rosenberg C, Okamoto OK. High OCT4A levels drive tumorigenicity and metastatic potential of medulloblastoma cells. Oncotarget. 2017 Mar 21;8(12):19192-19204. doi: 10.18632/oncotarget.15163. PubMed PMID: 28186969; PubMed Central PMCID: PMC5386677.

63. Suemoto CK, Ferretti-Rebustini RE, Rodriguez RD, Leite RE, Soterio L, Brucki SM, Spera RR, Cippiciani TM, Farfel JM, Chiavegatto Filho A, Naslavsky MS, Zatz M, Pasqualucci CA, Jacob-Filho W, Nitrini R, Grinberg LT. Neuropathological diagnoses and clinical correlates in older adults in Brazil: A cross-sectional study. PLoS Med. 2017 28;14(3):e1002267. doi: 10.1371/journal.pmed.1002267. eCollection 2017 Mar 28.

64. Thibes, RB, Novaes, NP; Lucato, LT, Campanholo, KR, Melo, Luciano M.; Leite, Claudia C, Amaro Jr E; Barbosa, ER; Bor-Seng-Shu, E, Cardosos, EF, Sato J R. Altered functional connectivity between precuneus and motor systems in Parkinson’s disease patients. Brain Connect. 2017 Dec;7(10):643-647. doi: 10.1089/brain.2017.0534. Epub 2017 Nov 30

65. Thomas AM , F.P. Lima, L.M.S. Moura, A.M. da Silva; E. Dias-Neto, Setubal JC. Comparative Metagenomics. Methods in Molecular Biology, v. 1704, pp. 243-260. Springer New York, 2018.

66. Vieira NM, Spinazzola JM , Alexander MS, Moreira YB , Kawahara G, Gibbs DE^, Mead LC, Verjovski-Almeida S, Zatz M, Kunkel LM. Repression of phosphatidylinositol transfer protein alpha ameliorates the pathology of Duchenne muscular dystrophy . Proc Natl Acad Sci U S A. 2017 6;114(23):6080-6085

67. Wyatt EJ, Demonbreun AR, Kim EY, Puckelwartz MJ, Vo AH, Dellefave-Castillo LM, Gao QQ, Vainzof M, Pavanello RCM, Zatz M, McNally EM. Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers. JCI Insight. 2018 May 3;3(9). pii: 99357. doi: 10.1172/jci.insight.99357. [Epub ahead of print]

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