INCT

Publicações dos pesquisadores do INCT Envelhecimento e Doenças Genéticas

Julho de 2019 a junho de 2020

1. Aguiar TFM, Rivas MP, Costa S, Maschietto M, Rodrigues T, Sobral de Barros J, Barbosa AC, Valieris R, Fernandes GR, Bertola DR , Cypriano M, Caminada de Toledo SR, Major A, Tojal I, Apezzato MLP, Carraro DM, Rosenberg C, Lima da Costa CM, Cunha IW, Sarabia SF, Terrada DL, Krepischi ACV. Insights Into the Somatic Mutation Burden of Hepatoblastomas From Brazilian Patients. Front Oncol. 2020 May 5;10:556

2. Al Assal K, Prifti E, Belda E, Sala P, Clément K, Dao MC, Doré J, Levenez F, Taddei CR, Fonseca DC, Rocha IM, Balmant BD, Thomas AM, Santo MA, Dias-Neto E, Setubal JC, Zucker JD, Belarmino G, Torrinhas RS, Waitzberg DL. Gut Microbiota Profile of Obese Diabetic Women Submitted to Roux-en-Y Gastric Bypass and Its Association with Food Intake and Postoperative Diabetes Remission. Nutrients. 2020 Jan 21;12(2):278. doi: 10.3390/nu12020278.

3. Almeida CF, Vainzof M. Skeletal Muscle Injury by Electroporation: A Model to Study Degeneration/Regeneration Pathways in Muscle. Methods Mol Biol. 2020;2063:157-169. doi: 10.1007/978-1-0716-0138-9_12.

4. Alves LC, Andrade FCD, Corona LP, Santos JLF, Duarte YAO. Inequalities in Life Expectancy With Frailty Among Brazilian Older Adults: A Multistate Approach. Innov Aging. 2019 Sep 4;3(4):igz032. doi: 10.1093/geroni/igz032. eCollection 2019 Aug.PMID: 31528717

5. Alvizi L, Brito LA, Bischain B, da Silva CBF, Ramos SLG, Kobayashi GS, Wang J, Passos-Bueno MR. mir152 hypomethylation, potentially triggered by embryonic hypoxia, as a common mechanism for non-syndromic cleft lip/palate. BioRxiv. doi: https://doi.org/10.1101/850016

6. Aoi H, Mizuguchi T, Ceroni JR, Kim VEH, Furquim I, Honjo RS, Iwaki T, Suzuki T, Sekiguchi F, Uchiyama Y, Azuma Y, Hamanaka K, Koshimizu E, Miyatake S, Mitsuhashi S, Takata A, Miyake N, Takeda S, Itakura A, Bertola DR, Kim CA, Matsumoto N. Comprehensive genetic analysis of 57 families with clinically suspected Cornelia de Lange syndrome. J Hum Genet. 2019 Oct;64(10):967-978.

7. Baran LCP, a Costa MF, Vidal  KS, Damico FM, Barboni MTS, Lima DS, França VCRM, Martins CMG, Tabares HS, Dias SL, Silva LA, Decleva D, Hamer RD, Zatz M, Bertozzi APAP, Gazeta RE, Passos SD, Ventura DF. Alterations in visual acuity and visual development in infants 1-24 months old either exposed to or infected by Zika virus during gestation, with and without microcephaly . J AAPOS. 2019 Aug;23(4):215.e1-215.e7. doi: 10.1016/j.jaapos.2019.03.005. Epub 2019 Jun 20.

8. Barrozo LV, Fornaciali M, de André CDS, Morais GAZ, Mansur G, Cabral-Miranda W, de Miranda MJ, Sato JR, Amaro Júnior E. GeoSES: A socioeconomic index for health and social research in Brazil. PLoS One. 2020 Apr 29;15(4):e0232074. doi:10.1371/journal.pone.0232074. eCollection 2020.

9. Boton Pereira DH, Primo LS, Pelizari G, Flores E, de Moraes-Vasconcelos D, Condino-Neto A, Prestes-Carneiro LE. Primary Immunodeficiencies in a Mesoregion of São Paulo, Brazil: Epidemiologic, Clinical, and Geospatial Approach. Front Immunol. 2020 May 12;11:862. doi: 10.3389/fimmu.2020.00862. eCollection 2020.

10. Braga SP, Dos Santos AP, Paganini T, Barbosa D, Epamino GWC, Morais C, Martins LF, Silva AM, Setubal JC, Vallim MA, Pascon RC. First report of cis-1,4-polyisoprene degradation by Gordonia paraffinivorans. Braz J Microbiol. 2019 Oct;50(4):1051-1062. doi: 10.1007/s42770-019-00143-w. Epub 2019 Aug 22.

11. Cabral-Marques O, Schimke LF, de Oliveira EB Jr, El Khawanky N, Ramos RN, Al-Ramadi BK, Segundo GRS, Ochs HD, Condino-Neto A. Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases With Immune Dysregulation. Front Immunol. 2019 Nov 26;10:2742. doi: 10.3389/fimmu.2019.02742. eCollection 2019.

12. Caneschi WL, Sanchez AB, Felestrino ÉB, Lemes CGC, Cordeiro IF, Fonseca NP, Villa MM, Vieira IT, Moraes LÂG, Assis RAB, do Carmo FF, Kamino LHY, Silva RS, Ferro JA, Ferro MIT, Ferreira RM, Santos VL, Silva UCM, Almeida NF, Varani AM, Garcia CCM, Setubal JC, Moreira LM. Serratia liquefaciens FG3 isolated from a metallophyte plant sheds light on the evolution and mechanisms of adaptive traits in extreme environments. Sci Rep. 2019 Nov 29;9(1):18006. doi: 10.1038/s41598-019-54601-4.

13. Carvalho MUWB, Vendramini P, Kubo CA, Soreiro-Pereira PV, de Albuquerque RS, Antunes E, Condino-Neto A. BAY 41-2272 inhibits human T lymphocyte functions. Int Immunopharmacol. 2019 Dec;77:105976. doi: 10.1016/j.intimp.2019.105976. Epub 2019 Nov 13.

14. Chaves JCS, Machado FT, Almeida MF, Bacovsky TB, Ferrari MF. microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. Neurosci Lett. 2020 Jan 1;714:134541. doi: 10.1016/j.neulet.2019.134541. Epub 2019 Oct 9

15. Cotta A, Paim JF, Carvalho E, Valicek J, da Cunha Junior AL, Navarro MM, Vargas AP, Lima MI, de Almeida CF, Takata RI, Vainzof M. LMNA-Related Muscular Dystrophy with Clinical Intrafamilial Variability. J Mol Neurosci. 2019 Dec;69(4):623-627. doi: 10.1007/s12031-019-01390-0. Epub 2019 Aug 13.

16. da Silva Montenegro EM, Costa CS, Campos G, Scliar M, de Almeida TF, Zachi EC, Silva IMW, Chan AJS, Zarrei M, Lourenço NCV, Yamamoto GL, Scherer S, Passos-Bueno MR. Meta-Analyses Support Previous and Novel Autism Candidate Genes: Outcomes of an Unexplored Brazilian Cohort. Autism Res. 2020 Feb;13(2):199-206. doi: 10.1002/aur.2238. Epub 2019 Nov 6.

17. de Albuquerque JAT, Lima AM, de Oliveira Junior EB, Ishizuka EK, Aragão-Filho WC, Bengala Zurro N, Mayumi Chiba S, Fernandes FR, Condino-Neto A. A Novel Mutation in the NCF2 Gene in a CGD Patient With Chronic Recurrent Pneumopathy. Front Pediatr. 2019 Sep 27;7:391. doi: 10.3389/fped.2019.00391. eCollection 2019.

18. Dufner-Almeida LG, Cruz DBD, Mingroni Netto RC, Batissoco AC, Oiticica J, Salazar-Silva R. Stem-cell therapy for hearing loss: are we there yet? Braz J Otorhinolaryngol. 2019 Jul - Aug;85(4):520-529. doi: 10.1016/j.bjorl.2019.04.006. Epub 2019 May 18. Review.

19. Fekrvand S, Yazdani R, Olbrich P, Gennery A, Rosenzweig SD, Condino-Neto A, Azizi G, Rafiemanesh H, Hassanpour G, Rezaei N, Abolhassani H, Aghamohammadi A. Primary Immunodeficiency Diseases and Bacillus Calmette-Guérin (BCG)-Vaccine-Derived Complications: A Systematic Review. J Allergy Clin Immunol Pract. 2020 Apr;8(4):1371-1386. doi: 10.1016/j.jaip.2020.01.038. Epub 2020 Jan 30.

20. Fernandes SA, Almeida CF, Souza LS, Lazar M, Onofre-Oliveira P, Yamamoto GL, L Nogueira , Tasaki LY, Cardoso RR, Pavanello RCM, Silva HCA, Ferrari MF, Bigot A, Mouly V, Vainzof M. Altered in vitro muscle differentiation in X-linked myopathy with excessive autophagy. Dis Model Mech. 2020 Jan 10;13(2). pii: dmm041244. doi: 10.1242/dmm.041244.

21. Galvão CRC, Cavalcante PMA, Olinda R, Graciani Z, Zatz M, Kok F, Santos S, Lancman S. Motor impairment in a rare form of spastic paraplegia (Spoan syndrome): a 10-year follow-up. BMC Neurol. 2019 Oct 27;19(1):256. doi: 10.1186/s12883-019-1465-5.

22. Godoy JAP, Paiva RMA, Souza AM, Kondo AT, Kutner JM, Okamoto OK. Clinical Translation of Mesenchymal Stromal Cell Therapy for Graft Versus Host Disease . Front Cell Dev Biol. 2019 Nov 21;7:255. doi: 10.3389/fcell.2019.00255. eCollection 2019. Review.

23. Gomes, F,C, Melo-Neto JS, Ferrari MF, Carlos, C,P, Goloni-Bertollo EM, Pavarino EC. Vitamin D3 increases the caspase-3 p12, MTHFR, and p-glycoprotein reducing amyloid-beta 42 in the kidney of a mouse model for Down syndrome . Life Sci. 2019 Aug 15;231:116537. doi: 10.1016/j.lfs.2019.06.012. Epub 2019 Jun 6.

24. Goulart E, Caires-Junior LC, Telles-Silva KA, Araujo BHS, Kobayashi GS, Musso CM, Assoni AF, Oliveira D, Caldini E, Gerstenhaber JA, Raia S, Lelkes PI, Zatz M. Adult and iPS-derived Non-Parenchymal Cells Regulate Liver Organoid Development Through Differential Modulation of Wnt and TGF-β. 2019 Aug 15;10(1):258. doi: 10.1186/s13287-019-1367-x

25. Goulart E, de Caires-Junior LC, Telles-Silva KA, Araujo BHS, Rocco SA, Sforca M, de Sousa IL, Kobayashi GS, Musso CM, Assoni AF, Oliveira D, Caldini E, Raia S, Lelkes PI, Zatz M. 3D bioprinting of liver spheroids derived from human induced pluripotent stem cells sustain liver function and viability in vitro. Biofabrication. 2019 Nov 27;12(1):015010. doi: 10.1088/1758-5090/ab4a30.

26. Griesi-Oliveira K, Fogo MS, Pinto BGG, Alves AY, Suzuki AM, Morales AG, Ezquina S, Sosa OJ, Sutton GJ, Sunaga-Franze DY, Bueno AP, Seabra G, Sardinha L, Costa SS, Rosenberg C, Zachi EC, Sertie AL, Martins-de-Souza D, Reis EM, Voineagu I, Passos-Bueno MR. Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder. Mol Psychiatry. 2020 Feb 14. doi: 10.1038/s41380-020-0669-9. [Epub ahead of print]

27. Griesi-Oliveira K, Passos-Bueno MR. Reply to Lombardo, 2020: An additional route of investigation: what are the mechanisms controlling ribosomal protein genes dysregulation in autistic neuronal cells? Mol Psychiatry. 2020 May 28. doi: 10.1038/s41380-020-0792-7. Online ahead of print.PMID: 32467646 No abstract available.

28. Guimarães Marques MJ, Real CC, Victorino DB, Britto LR, Cavalheiro EA, Scorza FA, Ferraz HB, Scorza CA. Endogenous protection against the 6-OHDA model of Parkinson's disease in the Amazonian rodent Proechimys. Neurosci Lett. 2019 Sep 14;709:134381. doi: 10.1016/j.neulet.2019.134381. Epub 2019 Jul 17.

29. Homma TK, Freire BL, Honjo Kawahira RS, Dauber A, Funari MFA, Lerario AM, Nishi MY, Albuquerque EV, Vasques GA, Collett-Solberg PF, Miura Sugayama SM, Bertola DR, Kim CA, Arnhold IJP, Malaquias AC, Jorge AAL. Genetic Disorders in Prenatal Onset Syndromic Short Stature Identified by Exome Sequencing. J Pediatr. 2019 Dec;215:192-198.

30. Homma TK, Freire BL, Honjo R, Dauber A, Funari MFA, Lerario AM, Albuquerque EVA, Vasques GA, Bertola DR, Kim CA, Malaquias AC, Jorge AAL. Growth and Clinical Characteristics of Children with Floating-Harbor Syndrome: Analysis of Current Original Data and a Review of the Literature. Horm Res Paediatr. 2019;92(2):115-123.

31. Jacobacci F, Jovicich J, Lerner G, Amaro E Jr, Armony JL, Doyon J, Della-Maggiore V. Improving Spatial Normalization of Brain Diffusion MRI to Measure Longitudinal Changes of Tissue Microstructure in the Cortex and White Matter. J Magn Reson Imaging. 2020 Feb 14. doi: 10.1002/jmri.27092. Online ahead of print.

32. Kaid C, Assoni A, Marçola M, Semedo-Kuriki P, Bortolin RH, Carvalho VM, Okamoto OK. Proteome and miRNome profiling of microvesicles derived from medulloblastoma cell lines with stem-like properties reveals biomarkers of poor prognosis. Brain Res. 2020 Mar 1;1730:146646. doi: 10.1016/j.brainres.2020.146646. Epub 2020 Jan 7. Review.

33. Kaid C, Jordan D, Bueno HMS, Araujo BHS, Assoni A, Okamoto OK. miR-367 as a therapeutic target in stem-like cells from embryonal central nervous system tumors. Mol Oncol. 2019 Aug 11. doi: 10.1002/1878-0261.12562. [Epub ahead of print]

34. Kaid C, Madi RADS, Astray R, Goulart E, Caires-Junior LC, Mitsugi TG, Moreno ACR, Castro-Amarante MF, Pereira LR, Porchia BFMM, de Andrade TO, Landini V, Sanches DS, Pires CG, Tanioka RKO, Pereira MCL, Barbosa IN, Massoco CO, Ferreira LCS, Okamoto OK, Zatz M. Safety, Tumor Reduction, and Clinical Impact of Zika Virus Injection in Dogs with Advanced-Stage Brain Tumors. Mol Ther. 2020 May 6;28(5):1276-1286. doi: 10.1016/j.ymthe.2020.03.004. Epub 2020 Mar 10.

35. Lacerda-Pontes R, Gomes LN, Albuquerque RS, Soeiro-Pereira PV,Condino-Neto A. The extended understanding of chronic granulomatous disease. Curr Opin Pediatr. 2019 Dec;31(6):869-873. doi: 10.1097/MOP.0000000000000830.

36. Lezirovitz K, Vieira-Silva GA, Batissoco AC, Levy D, Kitajima JP, Trouillet A, Ouyang E, Zebajardi N, Sampaio-Silva J, Pedroso-Campos V, Nascimento LR, Sonoda CY, Borges VM, Vasconcelos LG, Beck RMO, Grasel SS, Jagger DJ, Grillet N, Bento RF, Mingroni-Netto RC, Oiticica J. A rare genomic duplication in 2p14 underlies autosomal dominant hearing loss DFNA58 . Hum Mol Genet. 2020 Apr 27. pii: ddaa075. doi: 10.1093/hmg/ddaa075. [Epub ahead of print]

37. Lima DDS, Baran LCP, Hamer RD, Costa MFD, Vidal KS, Damico FM, Barboni MTS, França VCRM, Martins CMG, Tabares HS, Dias SL, Silva LA, Decleva D, Zatz M, Bertozzi APAP, Gazeta RE, Passos SD, Ventura DF. Longitudinal visual acuity development in ZIKV-exposed children. J AAPOS. 2020 Jan 8. pii: S1091-8531(20)30006-9. doi: 10.1016/j.jaapos.2019.11.005. [Epub ahead of print]

38. Lima NCR, Melo TQ, Sakugawa AYS, Melo KP, Ferrari MFR . Restoration of Rab1 Levels Prevents Endoplasmic Reticulum Stress in Hippocampal Cells during Protein Aggregation Triggered by Rotenone. NEUROSCIENCE, v.419, p.5-13, 2019. https://doi.org/10.1016/j.neuroscience.2019.08.050

39. Louzada S, Algady W, Weyell E, Zuccherato LW, Brajer P, Almalki F, Scliar MO, Naslavsky MS, Yamamoto GL,Duarte YAO, Passos-Bueno MR, Zatz M, Yang, F; & Hollox, EJ. (2019). Structural variation of the malaria-associated human glycophorin A-B-E region. Cold Spring Harbor Laboratory. https://doi.org/10.1101/722371

40. Magdalon J, Mansur F, Teles E Silva AL, de Goes VA, Reiner O, Sertié AL. Complement System in Brain Architecture and Neurodevelopmental Disorders. Front Neurosci. 2020 Feb 5;14:23. doi: 10.3389/fnins.2020.00023. eCollection 2020. Review.

41. Martins Trevisan C, Naslavsky MS, Monfardini F, Wang J, Zatz M, Peluso C, Pellegrino R, Mafra F, Hakonarson H, Ferreira FM, Nakaya H, Christofolini DM, Montagna E, Crandall KA, Barbosa CP, Bianco B. Variants in the Kisspeptin-GnRH Pathway Modulate the Hormonal Profile and Reproductive Outcomes. DNA Cell Biol. 2020 Jun;39(6):1012-1022. doi: 10.1089/dna.2019.5165. Epub 2020 Apr 29

42. Mazzucchelli J, Aranda CS, Gouveia-Pereira M, Barreiros LA, Costa Carvalho BT, Condino-Neto A, de Moraes-Pinto MI. The panorama in diagnoses of severe combined immunodeficiency begins to change in Brazil. J Allergy Clin Immunol. 2020 Mar;145(3):1029. doi: 10.1016/j.jaci.2019.12.895. Epub 2020 Jan 16.

43. Momtazmanesh S, Ochs HD, Uddin LQ, Perc M, Routes JM, Vieira DN, Al-Herz W, Baris S, Prando C, Rosivall L, Abdul Latiff AH, Ulrichs T, Roudenok V, Aldave Becerra JC, Salunke DB, Goudouris E, Condino-Neto A, Stashchak A, Kryvenko O, Stashchak M, Bondarenko A, Rezaei N. All together to Fight COVID-19. Am J Trop Med Hyg. 2020 Jun;102(6):1181-1183. doi: 10.4269/ajtmh.20-0281.

44. Moosa S, Yamamoto GL, Garbes L, Keupp K, Beleza-Meireles A, Moreno CA, Valadares ER, de Sousa SB, Maia S, Saraiva J, Honjo RS, Kim CA, Cabral de Menezes H, Lausch E, Lorini PV, Lamounier A Jr, Carniero TCB, Giunta C, Rohrbach M, Janner M, Semler O, Beleggia F, Li Y, Yigit G, Reintjes N, Altmüller J, Nürnberg P, Cavalcanti DP, Zabel B, Warman ML, Bertola DR, Wollnik B, Netzer C. Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta. Am J Hum Genet. 2019 Oct 3;105(4):836-843.

45. Oliveira D, Morales-Vicente DA, Amaral MS, Luz L, Sertié AL, Leite FS, Navarro C, Kaid C, Esposito J, Goulart E, Caires L, Alves LM, Melo US, Figueiredo T,Okamoto OK, Verjovski-Almeida S, Zatz M. Different gene expression profiles in iPSC-derived motor neurons from ALS8 patients with variable clinical courses suggest mitigating pathways for neurodegeneration. Hum Mol Genet. 2020 Apr 13. pii: ddaa069. doi: 10.1093/hmg/ddaa069. [Epub ahead of print]

46. Onofre-Oliveira PCG, Vainzof M. Isolation and Characterization of Muscle-Derived Stem Cells from Dystrophic Mouse Models. Methods Mol Biol. 2020;2063:171-180. doi: 10.1007/978-1-0716-0138-9_13

47. Padovani de Souza K, Setubal JC, Ponce de Leon F de Carvalho AC, Oliveira G, Chateau A, Alves R. Machine learning meets genome assembly. Brief Bioinform. 2019 Nov 27;20(6):2116-2129. doi: 10.1093/bib/bby072.

48. Pinheiro DJLL, Oliveira LF, Souza INO, Brogin JAF, Bueno DD, Miranda IA, Da Poian AT, Ferreira ST, Figueiredo CP, Clarke JR, Cavalheiro EA, Faber J. Modulation in phase and frequency of neural oscillations during epileptiform activity induced by neonatal Zika virus infection in mice . Sci Rep. 2020 Apr 21;10(1):6763. doi: 10.1038/s41598-020-63685-2.

49. Pires SF, Tolezano GC, da Costa SS, Kawahira RSH, Kim CA, Rosenberg C, Teixeira ACB, Bertola DR, Krepischi ACV. Expanding the role of SETD5 haploinsufficiency in neurodevelopment and neuroblastoma . Pediatr Blood Cancer. 2020 Nov;67(11):e28376. doi: 10.1002/pbc.28376. Epub 2020 Aug 3

50. Rodrigues MAS, Rodrigues TP, Zatz M, Lebrão, ML;Duarte YA, Naslavsky MS, Nascimento, FBP; Amaro Junior E. Quantitative evaluation of brain volume among elderly individuals in São Paulo, Brazil: a population-based study . Radiologia Brasileira, 52(5), 293-298. Epub August 15, 2019. https://dx.doi.org/10.1590/0100-3984.2018.0074
 

51. Roman Lay AA, Ferreira do Nascimento C, Caba Burgos F, Larraín Huerta ADC, Rivera Zeballos RE, Pantoja Silva V, Duarte YAO. Gender Differences between Multimorbidity and All-Cause Mortality among Older Adults. Curr Gerontol Geriatr Res. 2020 Feb 19;2020:7816785. doi: 10.1155/2020/7816785. eCollection 2020.PMID: 32148480

52. Saida K, Kim CA, Ceroni JRM, Bertola DR, Honjo RS, Mitsuhashi S, Takata A, Mizuguchi T, Miyatake S, Miyake N, Matsumoto N. Hemorrhagic stroke and renovascular hypertension with Grange syndrome arising from a novel pathogenic variant in YY1AP1. J Hum Genet. 2019 Sep;64(9):885-890

53. Samogy-Costa CI, Varella-Branco E, Monfardini F, Ferraz H, Fock RA, Barbosa RHA, Pessoa ALS, Perez ABA, Lourenço N, Vibranovski M, Krepischi A, Rosenberg C, Passos-Bueno MR. A Brazilian cohort of individuals with Phelan-McDermid syndrome: genotype-phenotype correlation and identification of an atypical case. J Neurodev Disord. 2019 Jul 18;11(1):13. doi: 10.1186/s11689-019-9273-1.54. Sanabria V, Bittencourt S, de la Rosa T, Livramento J, Tengan C, Scorza CA, Cavalheiro EA, Amado D. Characterization of the estrous cycle in the Amazon spiny rat (Proechimys guyannensis). Heliyon. 2019 Dec 13;5(12):e03007. doi: 10.1016/j.heliyon.2019.e03007. eCollection 2019 Dec.

55. Satterstrom FK, Kosmicki JA, Wang J, Breen MS, De Rubeis S, An JY, Peng M, Collins R, Grove J, Klei L, Stevens C, Reichert J, Mulhern MS, Artomov M, Gerges S, Sheppard B, Xu X, Bhaduri A, Norman U, Brand H, Schwartz G, Nguyen R, Guerrero EE, Dias C; Autism Sequencing Consortium; iPSYCH-Broad Consortium, Betancur C, Cook EH, Gallagher L, Gill M, Sutcliffe JS, Thurm A, Zwick ME, Børglum AD, State MW, Cicek AE, Talkowski ME, Cutler DJ, Devlin B, Sanders SJ, Roeder K, Daly MJ, Buxbaum JD. Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism . Cell. 2020 Feb 6;180(3):568-584.e23. doi:10.1016/j.cell.2019.12.036. Epub 2020 Jan 23.*Passos-Bueno, MR is part of the ASC.

56. Scliar MO, Sant Anna HP, Santolalla ML, Leal TP, Araújo NM, Alvim I, Borda V, Magalhães, WC, Gouveia MH, Lyra R, Machado M, Michelin L, Rodrigues MR, Araújo GS, Kehdy FS, Zolini C, Peixoto SV, Luizon M, Lobo F, Naslavsky MS, Tarazona-Santos E. Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass- and fat mass-indexes . Cold Spring Harbor Laboratory. 2019 https://doi.org/10.1101/827311

57. Simões PSR, Zanelatto AO, Assis MC, Varella PPV, Yacubian EM, Carrete H, Centeno R, Araujo MS, Cavalheiro EA, Tersariol ILS, Motta G, Naffah-Mazzacoratti MDG. Plasma kallikrein-kinin system contributes to peripheral inflammation in temporal lobe epilepsy. J Neurochem. 2019 Aug;150(3):296-311. doi: 10.1111/jnc.14793. Epub 2019 Jul 10.

58. Thomas AM, Manghi P, Asnicar F, Pasolli E, Armanini F, Zolfo M, Beghini F, Manara S, Karcher N, Pozzi C, Gandini S, Serrano D, Tarallo S, Francavilla A, Gallo G, Trompetto M, Ferrero G, Mizutani S, Shiroma H, Shiba S, Shibata T, Yachida S, Yamada T, Wirbel J, Schrotz-King P, Ulrich CM, Brenner H, Arumugam M, Bork P, Zeller G, Cordero F, Dias-Neto E, Setubal JC, Tett A, Pardini B, Rescigno M, Waldron L, Naccarati A, Segata N. Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation. Nat Med. 2019 Dec;25(12):1948. doi: 10.1038/s41591-019-0663-4.

59. Trancozo M, Moraes MVD, Silva DA, Soares JAM, Barbirato C, Almeida MG, Santos LR, Rebouças MRGO, Akel AN Jr, Sipolatti V, Nunes VRR, Errera FIV, Aguena M, Passos-Bueno MR, Paula F. Osteogenesis imperfecta in Brazilian patients. Genet Mol Biol. 2019 Aug 15. pii: S1415-47572019005033102. doi: 10.1590/1678-4685-GMB-2018-0043.

60. Trevisan CM, Naslavsky MS, Monfardini F, Wang J, Zatz M, Peluso C, Pellegrino R, Mafra F, Hakonarson H, Ferreira FM, Nakaya H, Christofolini DM, Montagna E, Crandall KA, Barbosa CP, Bianco B. Variants in the Kisspeptin-GnRH Pathway Modulate the Hormonal Profile and Reproductive Outcomes. DNA Cell Biol. 2020 Apr 29. doi: 10.1089/dna.2019.5165. [Epub ahead of print]

61. Uchiyama Y, Kim CA, Pastorino AC, Ceroni J, Lima PP, de Barros Dorna M, Honjo RS, Bertola DR, Hamanaka K, Fujita A, Mitsuhashi S, Miyatake S, Takata A, Miyake N, Mizuguchi T, Matsumoto N. Primary immunodeficiency with chronic enteropathy and developmental delay in a boy arising from a novel homozygous RIPK1 variant . J Hum Genet. 2019 Sep;64(9):955-960.

62. van Zelm MC, Condino-Neto A, Barbouche MR. Editorial: Primary Immunodeficiencies Worldwide. Front Immunol. 2020 Jan 22;10:3148. doi: 10.3389/fimmu.2019.03148. eCollection 2019.

63. Zimpel CK, Patané JSL, Guedes ACP, de Souza RF, Silva-Pereira TT, Camargo NCS, de Souza Filho AF, Ikuta CY, Neto JSF, Setubal JC, Heinemann MB, Guimaraes AMS. Global Distribution and Evolution of Mycobacterium bovis Lineages. Front Microbiol. 2020 May 7;11:843. doi: 10.3389/fmicb.2020.00843. eCollection 2020.

64. Zurro NB, de Oliveira Junior EB, França TT, Dantas VM, Tavares de Albuquerque JA, Condino-Neto A. Correction to: Unusual Severe Seborrheic Dermatitis in Two Siblings with Autosomal Recessive Chronic Granulomatous Disease. J Clin Immunol. 2019 Nov;39(8):860. doi: 10.1007/s10875-019-00701-9.