New Science for Development Centers will seek solutions to society’s problems
Universities, research institutions and agencies of the São Paulo State Government will join forces in 15 new centers announced during a ceremony held to celebrate FAPESP’s 60th anniversary. The centers will address problems in areas ranging from human and animal health to the energy transition and climate change
Brazilian dataset of whole-genome sequences brings more diversity in international databases, study says
Whole-genome sequences of 1,171 elderly people living in São Paulo City were analyzed to detect mutations responsible for disease or that play a key role in healthy aging.
Whole-genome database will help refine diagnosis of genetic diseases in Brazil
Whole-genome sequences of 1,171 elderly people living in São Paulo City were analyzed to detect mutations responsible for disease or that play a key role in healthy aging
Treatment with injections of zika virus destroys brain tumors in mice without causing neurological damage
Experiments conducted at HUG-CELL showed that besides directly combating tumor cells, zika alerted the immune system to the presence of cancer. The study opens up prospects for the use of virotherapy for central nervous system tumors.
Study opens up prospects for using virotherapy to treat central nervous system tumors
Men are the main transmitters of the novel coronavirus, study suggests
The hypothesis was raised by scientists at HUG-CELL, on the basis of an epidemiological survey involving 1,744 Brazilian couples where at least one partner was infected
A lucky few seem 'resistant' to Covid-19. Scientists want to know why
In a paper accepted for publication in Nature Immunology, researchers from HUG-CELL and colleagues with the COVID Human Genetic Effort propose several potential sites in the genome that could govern resistance to SARS-CoV-2
Cell-mediated immunity is essential to prevent reinfection by the novel coronavirus, study suggests
HUG-CELL researchers studied the case of identical twins in which only one sibling was reinfected and developed complications after a second exposure to the virus
Study maps immune system genes involved in resistance to SARS-CoV-2
HUG-CELL research suggest that more frequent variants in the resistant spouses could lead to more efficient activation of NK cells, which are part of the innate immune system, the first barrier against infection
Researchers develop a technique to produce transplantable livers in the laboratory
A method created in Brazil by the Human Genome and Stem Cell Research Center could be used for large-scale production of livers for transplantation.
Brazilian researchers complete Latin America’s largest whole-genome sequencing of elderly people
Analysis of DNA from 1,171 over-sixties living in São Paulo will enable scientists to identify genetic mutations responsible for diseases or important to healthy aging, according to the authors of the study
Study reveals genetic factors that can make placenta less capable of protecting fetus from zika
Findings reported by Brazilian researchers in PLOS Neglected Tropical Diseases help explain why only some babies whose mothers are infected during pregnancy are born with microcephaly and other anomalies.
HUG-CELL researchers develop saliva-based COVID-19 diagnostic test
The new tests are based on RT-LAMP, a molecular technique widely used to diagnose infectious diseases caused by RNA viruses such as dengue, chikungunya, hepatitis A and zika
Researchers investigate genetic factors behind resistance or susceptibility to COVID-19
A study is being conducted to determine whether people who develop severe forms of the disease have risk genes and whether asymptomatic people or patients with only mild symptoms have protective genes.
Study identifies group of genes with altered expression in autism
The dysregulation appeared to affect communication among neurons in the subjects of the study. The discovery could improve diagnosis, which is currently based on the clinical analysis of symptoms.
Zika combats advanced-stage central nervous system tumors in dogs
The viral therapy was tested in three elderly animals with spontaneous brain tumors by a group of researchers at the HUG-CELL
Zika inhibits the proliferation of prostate cancer cells
Experiments performed by Brazilian scientists showed that Zika virus inhibits tumor cell proliferation even when inactivated by high temperature. The study was published in Scientific Reports
Researchers create functional mini-liver by 3D bioprinting
Technique developed at the HUG-CELL produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future.